Covid 19 Vaccines affect on IVF treatment cycles

Take a look at Prof. Orvieto's latest academic work in the fertility field

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Israel was at the forefront of the initial COVID 19 vaccination program and was the first country in the world to have a high vaccination rate. Prof Orvieto and the team investigated whether receiving a COVID-19 vaccine influence patients ‘cycle outcomes during IVF treatments. Patients cycle outcome was examined in a cycle before and after receiving the vaccine.

Here is what they found out:

  • In the present study, we could not demonstrate any detrimental effect of mRNA SARS-CoV-2vaccine on ovarian reserve/ oocytes (eggs) pool, as reflected by the similar response to ovarian stimulation- which is considered the " most reliable sign of decrease ovarian reserve.
  • In the present study, mRNA SARS-CoV-2 vaccine showed no detrimental effect on patients' total motile count (a sperm quality parameter).
  • In the present study we observed no influence of mRNA SARS-CoV-2vaccine on patients’ performance during their immediate subsequent IVF cycle, reflecting no detrimental effects of the vaccine on patients’ ovarian reserve, nor the developing gametes/embryos.

Our take home message:

Each donor coming to our clinic is encouraged to receive the mRNA SARS-CoV-2 vaccine to protect her health if she hasn't received it before. Vaccines are now provided in our clinic to assure easy-access and no wait for our donors.

References:

Orvieto R, Noach-Hirsh M, Segev-Zahav A, Haas J, Nahum R, Aizer A. Does mRNA SARS-CoV-2 vaccine influence patients’ performance during IVF-ET cycle? Reprod Biol Endocrinol. 2021;19(1):1–4.